• Detection of Merkel Cell Polyomavirus (MCPyV) DNA and Transcripts in Merkel Cell Carcinoma (MCC) 

      Passerini, Sara; Prezioso, Carla; Babini, Giulia; Ferlosio, Amedeo; Cosio, Terenzio; Campione, Elena; Moens, Ugo; Ciotti, Marco; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-29)
      Merkel cell polyomavirus (MCPyV) is the etiological agent of the majority of Merkel cell carcinoma (MCC): a rare skin tumor. To improve our understanding of the role of MCPyV in MCCs, the detection and analysis of MCPyV DNA and transcripts were performed on primary tumors and regional lymph nodes from two MCC patients: one metastatic and one non-metastatic. MCPyV-DNA was searched by a quantitative ...
    • Prevalence of MCPyV, HPyV6, HPyV7 and TSPyV in Actinic Keratosis Biopsy Specimens 

      Prezioso, Carla; Brazzini, Gabriele; Passerini, Sara; Di Fabio, Carlotta; Cosio, Terenzio; Bernardini, Sergio; Campione, Elena; Moens, Ugo; Pietropaolo, Valeria; Ciotti, Marco (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-18)
      To date, 14 human polyomaviruses (HPyVs) have been identified using high-throughput technologies. Among them, MCPyV, HPyV6, HPyV7 and TSPyV present a skin tropism, but a causal role in skin diseases has been established only for MCPyV as a causative agent of Merkel cell carcinoma (MCC) and TSPyV as an etiological agent of Trichodysplasia Spinulosa (TS). In the search for a possible role for ...